The effects of pre-operative carbohydrate loading on the metabolic response to surgery in a low resource setting
Sylvie Njong1,&, Elroy Patrick Weledji1, Alain Chichom1
1Faculty of Health Sciences, University of Buea, Cameroon
Sylvie Njong, Faculty of Health Sciences, University of Buea, Cameroon
the stress response to surgery involves catabolism and gluconeogenesis resulting
in postoperative hyper glycaemia. Post-operative hyper glycaemia is a risk
factor for postoperative complications and pre-operative fasting further
aggravates this response. A carbohydrate (CHO) drink instead of fasting is expected
decrease insulin resistance and reduce post-operative hyper glycaemia. The
aim of this study was to assess the effect of the reduction of the pre-operative
fasting period on post-operative hyper glycaemia and post-operative complications
in open surgery.
a hospital-based prospective case control study of 70 patients scheduled for elective surgery were sampled to either a case (carbohydrate loaded) or a control (FAST) group. Postoperative hyper glycaemia and complications were the primary and secondary outcomes reported.
70 patients were recruited with 35 patients per group. 40(57.14%) were females and 30(42.86%) were males. The mean blood glucose on the first postoperative day was significantly higher in those who fasted (146.20±38.36mg/dl) than in those who received the energy drink (123.06±26.64mg/dl), p = 0.004. Postoperative infections were significantly higher in the control group than in the CHO group (31.43%; and 8.57%; 95% C.I: 1.2275-19.4715) p = 0.033. The mean length of hospital stay was longer in the FAST (12.54days±15.08) than in the CHO (9.17days±12.65) group although the difference was not statistically significant p = 0.3145. The mean age, surgery type and mean duration of surgery were significant between groups but not upon logistic regression for significant clinical and demographic variables.
pre-operative CHO loading is effective and safe in reducing post-operative hyper glycaemia and infection in open general surgery even in low resource area.
The 3rd Africa Diabetes Congress, Yaounde, Cameroon (Yaounde)
Dates: 19 Apr 17 - 22 Apr 17
Venue: Yaounde Congress Hall
Organizers: Africa Diabetes Congress Limited
Contact person: Prof. Jean Claude Mbanya (email@example.com)