Impact of diabetes on the health-related quality of life and productivity of people with type 2 diabetes in Yaoundé, Cameroon: a cross-sectional study
Clarisse Mapa-Tassou1,&, Leopold Fezeu2, Zakariaou Njoumemi1, Jude Saji3, Eric Lontchi-Yimagou4, Jean-Claude Njabou Katte1, Eugene Sobngwi5,6, Jean-Claude Mbanya5,6
1Department of Public Health, Faculty of Medicine and Biomedical sciences, The University of Yaoundé I, Yaoundé, Cameroon, 2University of Paris 13, Sorbonne Paris Cité-UREN (Unité de Recherche en Epidémiologie Nutritionnelle), U557 Inserm; U1125 Inra; Cnam; CRNH IdF, F-93017 Bobigny, France, 3Institut de Recherche en Santé Publique, Université de Montréal, Montréal, QC, Canada, 4Diabetes Research and Training Centre and Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA, 5Department of Internal Medicine and specialties, Faculty of Medicine and Biomedical sciences, The University of Yaoundé I, Yaoundé, Cameroon, 6Laboratory for Molecular Medicine and Metabolism, Biotechnology Centre, University of Yaoundé I, Yaoundé, Cameroon
Clarisse Mapa-Tassou, Department of Public Health, Faculty of Medicine and Biomedical sciences, The University of Yaoundé I, Yaoundé, Cameroon
numerous studies have shown that diabetes reduces health-related quality of life (HRQoL), but little is known about the association between diabetes, HRQoL and productivity in developing countries. This study aimed toassess the impact of type 2 diabetes on the HRQoL and the ability to work of people with type 2 diabetes (T2D) in Yaoundé, Cameroon.
we conducted a cross-sectional study comparing the HRQoL and the ability to work, school and eat, in 500 people with T2D attending diabetes outpatient units of three hospitals in Yaoundé and 500 people without diabetes matched for age, sex and residence.We performed multivariate logistic and linear regressions to assess the effect of diabetes on HRQoL (using Health Utilities Index Mark 3 scores) andability to work. In analyzing the effect of diabetes on HRQoL, we adjusted HUI scores for socio-demographic characteristicsand the number of comorbidities.
the overall unadjusted HUI3 mean score was significantly lower in people
with T2D compared to people without diabetes (0.507 ± 0.333 vs. 0.725 ± 0.231,
p < 0.001); with nearly 7 times the clinically important difference of 0.03.
When adjusted for socio-demographic characteristics, HUI3 dimension mean
scores were lower for the eight dimensions of the HUI3 in people with T2D
was the main predictor for HRQoL (β -0.208 [95% CI: -0.266; -0.148]), p < 0.0001.
After adjustment for both socio-demographic characteristics and the number
of comorbidities, diabetes was still a good predictor for HRQoL (β -0.149
[95% CI: -0.211; -0.085]), p < 0.0001. People with T2D had 7 times more odds
of having at least one day lost from work, during the past 90 days, (OR 7.1
[95% CI: 4.1 - 11.9]), p < 0.001.
type 2 diabetes had a negative impact on the HRQoL and the ability to work
of people with diabetes in this African population, Cameroon. A better understanding
of the impact of diabetes on patients and families can be an important tool
for policy makers to undertake evidence-based actions.