Proceedings of 1st Ghana Field Epidemiology and Laboratory Training Programme Scientific conference (Accra, 2017)

Oral presentation

Evidence of non-influenza respiratory viruses among children under five years hospitalized with pneumonia, Greater Accra, 2013-2017

Cite this: Pan African Medical Journal - Conference Proceedings. Oct 2017; 3(3): 44. doi:10.11604/pamj.cp.2017.3.44.140

Submitted: 06 Oct 17   Accepted: 09 Oct 17   Published: 19 Oct 17

Key words: Pneumonia, children under five years, non-influenza respiratory viruses

© Elijah Paa Edu-Quansah et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.proceedings.panafrican-med-journal.com/conferences/2017/3/44/abstract

Corresponding author: Elijah Paa Edu-Quansah, Ghana Field Epidemiology and Laboratory Training Programme, Noguchi Memorial Institute for Medical Research, Ghana (paaeliquansah@gmail.com)

This abstract is published as part of the proceedings of 1st Ghana Field Epidemiology and Laboratory Training Programme Scientific conference (GHANA, )

Evidence of non-influenza respiratory viruses among children under five years hospitalized with pneumonia, Greater Accra, 2013-2017

Elijah Paa Edu-Quansah1,2,&, Bismark Sarfo1, Margaret Niezer3, Michael Addo Preko Ntiri2, Joseph Humphery Kofi Bonney2, Anthony Twumasi Boateng2, Doris Aboagyewaa Boampong2, William Kwabena Ampofo2

 

1Ghana Field Epidemiology and Laboratory Training Program, Ghana, 2Noguchi Memorial Institute for Medical Research, Ghana, 3Ghana Health Service, Ghana

 

 

&Corresponding author
Elijah Paa Edu-Quansah, Ghana Field Epidemiology and Laboratory Training Programme, Noguchi Memorial Institute for Medical Research, Ghana

 

 

Abstract

Introduction: acute respiratory illness contributes significantly to hospitalizations. It causes morbidity and mortality in younger children throughout the world, especially in developing countries. Pneumonia is a lower respiratory infection which causes inflammation of the lung parenchyma and leads to reduced oxygenation, shortness of breath and death. It is caused by a number of infectious agents which includes; viruses, bacteria and fungi. In 2015, pneumonia accounted for about 15% of deaths among children below five years, killing 920,136 children globally. Greater Accra records an estimated 16300 cases of pneumonia annually of which 40% are children under five years. Viral etiological agents responsible for pneumonia are not investigated, with treatment mostly focused on antibiotics. Against this introduction, this study sought to determine the contribution of non-influenza respiratory viruses (Respiratory syncytial virus, human para-influenza and adenovirus) in children under five years hospitalized with pneumonia in the Greater Accra region.

 

Methods: a laboratory-based cross sectional study was conducted where nasopharyngeal (NP) and oropharyngeal (OP) specimen were obtained from children under five years hospitalized with pneumonia in two three health facilities. Specimen were tested via reverse transcription polymerase chain reaction (RT PCR). Data were entered into a Microsoft visual basic interface linked to SQL database. Analysis was performed using STATA v13 and data presented in proportions and charts.

 

Results: a total of 238 nasopharyngeal and oropharyngeal swabs were obtained children under five years hospitalized with pneumonia from February 2013 through to April 2017. The mean age of the participants was 14 months (+/- 13months), ranging from 2 to 58months, with 51.3% (122) males being the majority. A total of 60 (25.2%) tested positive for at least one of respiratory syncytial virus, adenovirus, human para-influenza virus 1 and 3. Relatively 39 (16.4%) were positive for RSV, 11 (4.6%) for adenovirus, 8 (3.4%) HPIV-3 and 5 (2.1%) HPIV-1.

 

Conclusion: the study demonstrated the presence of non-influenza respiratory virus namely; RSV, HPIV-1, HPIV-3 and Adenoviruses among children under five years hospitalized with pneumonia in Greater Accra. Hence, non-investigation of these viruses before treatment with antibiotics could lead to a gap in proper patient management.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1st Ghana Field Epidemiology and Laboratory Training Programme Scientific conference (Accra)

Country: GHANA

Dates: 18 Sep 17 - 21 Sep 17

Venue: Swiss Spirit and Suites Alisa Hotels

Organizers: Ghana Field Epidemiology and Laboratory Training Programme

Secretariat: gfeltp@gmail.com

Contact person: Dr. Ernest Kenu (ernest_kenu@yahoo.com)