Factors associated with tuberculosis treatment outcomes in Opuwo District Hospital-
Kunene Region, Namibia 2013-2015
Silas Nghishihange1, Kofi Nyarko1,&, Micheal Shikongo1, Ligola Akwenye1
1Namibia Field Epidemiology and Laboratory Training Program, Windhoek, Namibia
Kofi Nyarko, Namibia Field Epidemiology and Laboratory Training Program, Windhoek, Namibia
globally, tuberculosis (TB) causes about 1.5 million deaths annually. Namibia is among the high burden TB countries with high mortality rates (33/100 000). Tuberculosis is curable; however, treatment outcomes can be influenced by various factors. We conducted a study to describe patients on anti-TB medication and to identify factors associated with poor treatment outcomes in Opuwo District Hospital, 2013-2015.
we conducted a descriptive, cross sectional study by reviewing TB patientís treatment cards from 2013-2015. Data were described in respect of person, place and time. We generated frequencies and proportions. Chi-square test of significance was used to determine association at p-value < 0.05. Logistic regression was performed to determine factors associated with treatment outcomes and the results were presented as Odds Ratio with 95% confidence interval.
a total of 358 patients were on TB treatment with the case fatality of 6%
(n = 21). The majority 53% (191/358) were males while 47% (167/358) females.
The mean age of patients who were on treatment was 35 years, (SD 17, 6),
ranged from (1-84) years. Most patients on treatment were from rural areas 71%
Of 358, 26% (n = 92) patients have completed treatment while 13% (48/358)
were lost to follow up. Lost to follow was significantly higher among rural
compare to urban residents, (OR = 5, 95% CI: 1.18-21.0). Being employed was
protective against loss to follow up compare to those who were unemployed
(OR = 0.3, 95% CI: 0.15-0.58). Dying from TB while on treatment was associated
TB co-infected with HIV, (OR = 4.0, 95% CI: 1.7-10.23).
employment status, HIV status and residential addresses were associated with tuberculosis treatment outcome. Health education on importance of TB treatment adherence was conducted. We recommend a comprehensive study to determine the factor associated with lost to follow up among TB patient.
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