Proceedings of 1st International Military Congress of Tropical Medicine and Sub-Saharan Diseases (Gabès, 2017)

Abstract

Tuberculosis occurring in adult idiopathic pulmonary hemosiderosis

Cite this: Pan African Medical Journal - Conference Proceedings. Dec 2017; 4(4): 153. doi:10.11604/pamj.cp.2017.4.153.361

Submitted: 19 Oct 17   Accepted: 03 Nov 17   Published: 05 Dec 17

Key words: Tuberculosis, idiopathic pulmonary hemosiderosis, Tunisia

© Nesrine Belgacem et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.proceedings.panafrican-med-journal.com/conferences/2017/4/153/abstract

Corresponding author: (belgacemnesrine@gmail.com)

This abstract is published as part of the proceedings of 1st International Military Congress of Tropical Medicine and Sub-Saharan Diseases(TUNISIA, )

Tuberculosis occurring in adult idiopathic pulmonary hemosiderosis

Nesrine Belgacem1,&, Najla Lassoued1, Hassène Baïli1, Safa Trabelsi1, Maher Béji1, Salem Bouomrani1

 

1Department of Internal Medicine, Gabès Military Hospital, Gabès, Tunisia

 

 

&Corresponding author
Nesrine Belgacem, Department of Internal Medicine, Gabès Military Hospital, Gabès, Tunisia

 

 

Abstract

Introduction: idiopathic pulmonary hemosiderosis (IPH) is an exceptional chronic respiratory disorder of unknown etiology. Its prevalence is estimated at 0.24 to 1.23 cases per million and nearly 80% of the cases manifest before the age of 10. Adult forms are very rare. We describe here the case of pulmonary tuberculosis occurring in adult patient with IPH.

 

Methods: a 20-year-old woman was explored for recurrent hemoptysis, stage II dyspnea and chronic cough. Laboratory tests showed a microcytic and hypochromic hyposideremic anemia without other anomalies. X-rays and chest CT scans showed bilateral and diffuse alveolar-interstitial syndrome. Broncho alveolar lavage was suggesting an intra-alveolar hemorrhage. Systemic disease, vasculitis and severe infections were excluded and the diagnosis of IPH was confirmed by lung biopsy revealing hemosiderin-laden macrophages in the alveoli.

 

Results: the patient received systemic glucocorticoids with a good and total response. Eight months later she was admitted because of fever, hemoptysis, marked inflammatory syndrome and leucopenia. Chest radiography and tomography were non-contributory. Bronchofibroscopy with direct exam for mycobacterium tuberculosis was positive. Under anti-tubercular therapy, the evolution was favorable.

 

Conclusion: lung tuberculosis associated to idiopathic pulmonary hemosiderosis is very rare. Immunodeficiency, corticotherapy as well as the underlying pulmonary lesions can support such an association.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1st International Military Congress of Tropical Medicine and Sub-Saharan Diseases ()

Country: TUNISIA

Dates: 23 Oct 16 - 25 Oct 16

Venue:

Organizers:

Secretariat: dgsante_cmed@defense.tn

Contact person: Pr Salem Bouomrani (Salembouomrani@yahoo.fr)