Lagos bat virus infection study
Richard Suu-Ire1,2,&, Yaa Ntiamoah-Baidu1, Andrew Cunningham3, James Wood4
1University of Ghana, Legon, Accra, Ghana, 2Veterinary Service Department, Accra, Ghana, 3Institute of Zoology, Zoological Society of London, London, United Kingdom, 4Department of Veterinary Medicine, Disease Dynamics Unit, University of Cambridge, Cambridge, United Kingdom
Richard Suu-Ire, Veterinary Service Department, Accra, Ghana
bats are reservoirs for many emerging and neglected zoonotic viruses, including rabies virus, Severe Acute Respiratory Syndrome (SARS) like coronavirus, henipavirus and filovirus. Fruit bats of several species are reservoir hosts for Lagos Bat Virus (LBV) with spillover infections documented in dogs, cats and mongoose. The impact of bat lyssavirus in Africa is unknown.
investigations of the dynamics of zoonotic viruses in wild bats in Ghana identified lyssaviruses (LBV), henipaviruses and filoviruses (Ebola) as zoonotic infections of fruits bats in Ghana. LBV has not been well studied and its risk for human and animals uncertain. We hypothesized that the inoculation of LBV can cause clinical disease in E. helvum.
to investigate the pathobiology and transmission pattern of LBV in fruits bats, we conducted experimental intracranial inoculation (i.c) of LBV in captive bred and seronegative for Lagos bat virus, straw colored fruits bats (Eidolon helvum) in Accra, Ghana. All 12 infected bats developed clinical rabies. All the infected bats died or were euthanized due to welfare concern within one (1) week of infection. All control bats survived till the end of the experiment.
we concluded that intracranial inoculation of Lagos bat virus can cause fatal disease in bats. This paper present the clinical features of the infection study.
The 2nd International Conference on Rabies in West Africa (RIWA) (Madina)
Rabies in West Africa, a forum to coordinate regular meeting among governments and stakeholders in one-health, was inaugurated in December, 2012 to link Anglophone and Francophone West African countries in the surveillance and control of rabies. It aims to disseminate progress reports on rabies surveillance and control activities in West Africa. Its first conference was jointly sponsored by the Federal Ministry of Health, Nigeria and the University of Ibadan Centre for Control and Prevention of Zoonoses. The 2nd conference was held concurrently with the 20th Congress of the Ghana Veterinary Medical Association. The scientific programme included 2 lead papers, 9 symposia and a roundtable discussion. The presented papers which focused on: (i) knowledge, attitude and practices among native community stakeholders; (ii) clinical detection and outbreak investigations; (iii) national laboratory diagnostic activities and vaccination records; (iv) wildlife infection study; and (v) spatial or spatio-temporal distribution of dog bite victims with suspected, probable and confirmed rabies exposures from three countries namely, Ghana (7); Nigeria (4) and Liberia (1). The conference gave consensus report that rabies has remained a neglected disease in West Africa and therefore deserves one-health approach for its control and prevention alongside a stepwise eradication in domestic dogs and humans.
Dates: 28 Oct 14 - 31 Oct 14
Venue: Institute of Local Government Studies
Organizers: The Society for Rabies in West Africa
Contact person: Professor Albert B. Ogunkoya (firstname.lastname@example.org)