Conference abstract

Antibiotic susceptibility pattern for bacteria pathogens isolated in urinary tract infection, Tamale, Ghana, 2017

Pan African Medical Journal - Conference Proceedings. 2017:3(43).19 Dec 2017.
doi: 10.11604/pamj-cp.2017.3.43.141

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Keywords: Urinary tract infection, antibiotic susceptibility, laboratory data
Oral presentation

Antibiotic susceptibility pattern for bacteria pathogens isolated in urinary tract infection, Tamale, Ghana, 2017

Gyesi Razak Issahaku1,2,&, Aaron Naah-Sabie2, Amin Iddrisu Kpani2, Donne Ameme1, Ernest Kenu1, Samuel Oko Sackey1, Priscillia Nortey1, Edwin Andrew Afari1

1Ghana-Field Epidemiology and Laboratory Training Program, Ghana, 2Ghana Health Service, Ghana

&Corresponding author
Gyesi Razak Isshaku, Ghana-Field Epidemiology and Laboratory Training Program, Ghana Health Service, Ghana

Abstract

Introduction: urinary tract infection (UTI) has become a treatment burden on clinicians despite the widespread availability of antibiotics. Though it is one of the commonest conditions encountered in the hospitals, the appearance of pathogens with growing resistance to a majority of antimicrobial agents has become a common occurrence. This study aimed at determining the common bacterial isolates and the antibiotic susceptibility patterns in patients presenting with Urinary Tract Infection in the Tamale metropolis.

Methods: we abstracted and reviewed laboratory data from October 2016 to June 2017. We analyzed the data descriptively into frequencies and percentages as well as the median for continuous data. We analyzed the data using Microsoft Excel 2013 and Epi Info 7.

Results: a total of 1,006 cases of suspected urinary tract infection was reported within the period, 514 (51.09%) were males, and 154 (15.31%) were aged five years and below. The median age of the patients was 28 years (IQR 19 98 years). The prevalence of culture positive UTI in this population was 212 (21.07%) of which 185 (87.26%) grew gram-negative organisms. Escherichia coli was the most common organism; isolated from 53 (25%) patients with positive UTI cultures. It showed 29 (54.72%) sensitivity to Amikacin and 35 (66.04%) and 27 (50.94%) resistance to tetracycline and ciprofloxacin respectively. The predominant gram-positive organism isolated was Staphylococcus aureus isolated from 16 (7.55%) positive UTI cultures and showed 12 (57.14%) sensitivity to gentamicin.

Conclusion: gram-negative organisms were the commonest blood culture isolates from suspected UTI patients. Escherichia coli was the predominant isolate. There was high bacteria antibiotic resistance to tetracycline and ciprofloxacin. We recommended a review of tetracycline and ciprofloxacin as first-line drugs for the treatment of urinary tract infection.