Conference abstract

Isolation of uro-pathogenic bacteria and their antimicrobial susceptibility pattern in urine samples of patients with suspected urinary tract infection in Eastern Regional Hospital, Koforidua -Ghana, 2016

Pan African Medical Journal - Conference Proceedings. 2017:3(99).29 Dec 2017.
doi: 10.11604/pamj-cp.2017.3.99.211

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Keywords: Urinary tract infection, antibiotics, susceptibility, sensitivity, Eastern Regional Hospital
Oral presentation

Isolation of uro-pathogenic bacteria and their antimicrobial susceptibility pattern in urine samples of patients with suspected urinary tract infection in Eastern Regional Hospital, Koforidua -Ghana, 2016

Baba Kunta Fofana1,2,&, Bismark Sarfo2

1Edward Francis Small Teaching Hospital Banjul, Banjul, Gambia, 2University of Ghana, School of Public Health, Ghana

&Corresponding author
Baba Kunta Fofona, Edward Francis Small Teaching Hospital Banjul, Banjul, Gambia, University of Ghana, School of Public Health, Ghana

Abstract

Introduction: urinary tract infection (UTI) is a common bacterial infection known to affect the different parts of the urinary tract and the occurrence is found both in females and males. In uncomplicated UTI cases, the infection is easily treated with the course of antibiotic therapy, but there is high resistance to many of these antibiotics. The objective of this study was to determine the prevalence and antibiotic susceptibility pattern of Uro-pathogenic bacteria in urine samples of patients with suspected UTI at the Eastern Regional Hospital, Koforidua - Ghana.

Methods: this cross-sectional study was carried out at the Medical Microbiology Department of Eastern Regional Hospital, Koforidua‚, Ghana, over a three-month period (December 2015 to March 2016). A total of 422 urine samples were received for the investigations and the data entered into MS Excel 2-13. Univariable analysis was done for sex, age, distribution, yield and antibiotic susceptibility and the results displayed as proportions and percentages.

Results: in all, 422 urine samples were received and 22.5% (95/422) yielded uro-pathogens with the highest percentage yield in females, 79.0% (75/95) in whom all were between 32 years and 40 years. Of the 95 that yielded uro-pathogens, the commonest isolates were: E. coli 36 (37.9%) and Klebseilla spp. 33(34.7%). All the bacteria showed sensitivity to Amikacin and Nitrofurantoin, but resistance to Augmentin, Ampicillin, Co-trimoxazole and Gentamycin.

Conclusion: high level of bacterial resistance exist in the study area. Therefore, there is a need for regular local investigation and improved antibiotic stewardship.