Conference abstract

Measles outbreak investigation in Otodogbame Community, Eti-Osa LGA, Lagos State, Nigeria, February 2016

Pan African Medical Journal - Conference Proceedings. 2018:8(11).21 Dec 2018.
doi: 10.11604/pamj-cp.2018.8.11.593

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Keywords: Measles, outbreak, Lagos State, Nigeria
Opening ceremony

Measles outbreak investigation in Otodogbame Community, Eti-Osa LGA, Lagos State, Nigeria, February 2016

Oyeladun Funmi Okunromade1,&, Folasade Osundina1, Nurain Ayeola1, Hakeem Yusuff1, Musiliyu Agbalaya1, Hakeem Bisiriyu1, Saheed Gidado2, Patrick Nguku1

1Nigeria Field Epidemiology and Laboratory Training Program, Abuja, Nigeria, 2African Field Epidemiology Network (AFENET), Nigeria

&Corresponding author
Oyeladun Funmi Okunromade, Nigeria Field Epidemiology and Laboratory Training Program, Asokoro, Abuja, Nigeria

Abstract

Introduction: measles is a highly contagious vaccine preventable viral infection with high mortality and morbidity. Immunisation coverage as low as 20% were reported in Nigeria. Suspected Measles outbreak was reported in Otodogbame Community. We investigated to verify, characterize and determine risk factors associated with the mortality.

Methods: we conducted unmatched case-control study using IDSR case definition of Measles from December to February 2016 residing in Otodogbame Community. We interviewed 82 cases and 246 controls using an interviewer-administered questionnaire on socio-demographic information and risk factors for Measles. Anthropometric measurements of assessing children were taken. Malnutrition was defined as =2 standard deviation away from the WHO recommended Z-score table of weight for height. Independent risk factor for Measles mortality was determined by bivariate and multivariate analysis.

Results: a total of 82 cases and 246 controls were interviewed. Median ages for cases and controls were 42 months (range: 10-156) and 36 months (range: 9-108), Mortality was 30%, 269 (82%) were malnourished [OR = 2.9; 95% CI: 1.1-3.3)], failure to achieve DPT3 immunization [OR = 2.3; (95% CI: 1.4 - 3.7)], lack of formal education [OR = 1.9; (95% CI: 1.1-3.1)],maternal age < 30 years [OR = 1.9; (95% CI: 1.1-3.2)], spending > 500 naira on transport per vaccination visit [OR = 2.3; (95% CI: 1.3 - 4.1)] and family income <10,000 naira ($20) per month [OR = 2.1; (95% CI: 1.3-3.5)] were statistically significant risk factors for Measles disease on bivariate analysis. Multivariate analysis revealed failure to vaccinate for Measles [AOR = 2.3; (95% CI: 1.1-4.7)], failure to achieve DPT3 coverage [AOR =3.3; (95% CI: 1.7 - 6.4)], family earning < 10000 naira ($20) per month [AOR = 2.1; (95% CI: 1.3-3.5)], spending > 500 naira (>$2) per vaccination visit [AOR = 2.4; (95% CI: 1.2 - 4.6)] as independent risk factors for measles disease.

Conclusion: acute malnutrition, lack of easy access to a health facility, financial limitations in the family and low immunization coverage led to the high mortality. Effective RI delivery, improving the socio-economic status could reduce Measles mortality.