Conference abstract

Frequency of high blood pressure, dyslipidaemia and diabetes complications in type 1 (T1D) and type 2 (T2D) diabetes in Africa: results from the International Diabetes Management Practices Study (IDMPS)

Pan African Medical Journal - Conference Proceedings. 2021:11(41).01 Dec 2021.
doi: 10.11604/pamj-cp.2021.11.41.978

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Keywords: Africa, T1D, T2D, hypertension, dyslipidemia, complications
Abstract

Frequency of high blood pressure, dyslipidaemia and diabetes complications in type 1 (T1D) and type 2 (T2D) diabetes in Africa: results from the International Diabetes Management Practices Study (IDMPS)

Jean Claude Mbanya1,&, Hasan İlkova2, Juan José Gagliardino3, Pablo Aschner4, Fernando Lavalle5, Ambady Ramachandran6, Marina Shestakova7, Jean-Marc Chantelot8, Juliana Chung-Ngor Chan9

1Biotechnology Center, Doctoral School of Life Sciences, Health and Environment, and Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon, 2Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Endocrinology, Metabolism and Diabetes, Istanbul, Turkey, 3CENEXA, Center of Experimental and Applied Endocrinology (La Plata National University - La Plata National Scientific and Technical Research Council), La Plata, Argentina, 4Javeriana University School of Medicine and San Ignacio University Hospital, Bogotá, Colombia, 5Facultad de Medicina de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 6India Diabetes Research Foundation and Dr. A. Ramachandran's Diabetes Hospitals, Chennai, India, 7Endocrinology Research Center, Moscow, Russia, 8Sanofi, Paris, France, 9Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, China

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Introduction: appropriate disease management in people with diabetes requires control of both blood glucose levels and associated cardiovascular risk factors such as blood pressure and serum lipid profiles. We investigated the proportions of people with diabetes-associated high blood pressure (HBP) and abnormal lipid profiles and their control/treatment in Africa. Methods: the IDMPS is a global observational study of the management and patterns of care of people with T1D and T2D in the developing world. The proportions of people with HBP (> 130/80 mmHg) and abnormal lipid profiles (LDL-C ≥ 2.59 mmol/l) associated with diabetes were determined for participants enrolled from 12 countries across Africa between 2016-2017. Results: in people with T1D (N=788), 16.5% and 24.8% had HBP and abnormal lipid profiles, respectively. Rates were higher for people with T2D (N=2403), with 63.4% and 62.9% displaying HBP and abnormal lipid profiles respectively. Lack of SBP, DBP or LDL-C control was reported by 35.6%, 46.6% and 53.3% of people with T1D respectively; rates were higher for people with T2D, with 70.4%, 67.9% and 57.4% respectively reporting lack of SBP, DBP or LDL-C control. In total, only 2.3% of people with T1D and 3.1% of people with T2D achieved the triple target of HbA1c<7 %, BP <130/80 mmHg, and LDL-C <2.59 mmol/l overall. Microvascular/macrovascular complications were present in 38.7%/4.1% and 41.9%/11.4% of participants with T1D and T2D, respectively. Conclusion: improved control and treatment of both HBP and lipid abnormalities is essential (particularly in people with T2D) to reduce the burden of disease-induced complications.