Conference abstract

Amplitude and factors associated with intradialytic blood pressure variability: an example from a tertiary referral hospital in Cameroon

Pan African Medical Journal - Conference Proceedings. 2023:16(14).15 Mar 2023.
doi: 10.11604/pamj-cp.2023.16.14.1872
Archived on: 15 Mar 2023
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Keywords: Amplitude, variation, blood pressure, hemodialysis, Douala
Oral presentation

Amplitude and factors associated with intradialytic blood pressure variability: an example from a tertiary referral hospital in Cameroon

Ebene Romain1, Anastase Dzudie Tamdja2,3, Hermine Fouda2,3, Sidick Mouliom1,2, Ngamby Vincent1,4, Sena Penda1, Ladé Viché1,2, Félicité Kamdem1,2, Marie Patrice Halle1,2,&

1Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon, 2Department of Internal Medicine, Douala General Hospital, Douala, Cameroon, 3Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon, 4Department of Internal Medicine, Laquintinie Hospital of Douala, Douala, Cameroon

&Corresponding author

Introduction: Blood pressure variability (BPV) is a frequent complication during hemodialysis. Our aim was to determine the amplitude and the factors associated with intradialytic blood pressure variability amongst patients with kidney failure on chronic hemodialysis in Cameroon.

Methods: a cross-sectional analytic study was conducted at the Douala General Hospital, including consenting patients aged over 18 years on hemodialysis for more than 3 months. We excluded those with an acute complication before dialysis which could modify the blood pressure. Data collected were socio-demographic and clinical. Each patient was followed on one hemodialysis session during which five blood pressure measurements were taken hourly. We assessed the intra-dialytic BPV using Blood Pressure average real variability (ARV). Values above the median were considered abnormal variations. Statistical analysis was performed using SPSS 25.0 software with significance defined as p-value < 0.05.

Results: one hundred and sixty-nine (169) patients were included with 69.23% being male. The mean age was 47.68 (13.76) years. The main comorbidities were hypertension (94.67%) and diabetes (15.98%). The median (min-max) hourly change in systolic BP was 11.50 (8.00-16.50) mmHg. Patients with abnormal amplitude of variation accounted for 49.7% and the independently associated factors were: age ≥ 70 years, high blood pressure, the use of antihypertensive medication, dialysis vintage ≥ 5 years, and ultrafiltration rate ≥ 850 ml/h.

Conclusion: the amplitude of variation in intradialytic systolic BP was high with a significant prevalence of abnormal variation; associated factors related mainly to the patient's comorbidities and lifestyle.