Conference abstract

Viral co-infection with human respiratory syncytial virus in suspected acute and severe respiratory tract infections during COVID-19 pandemic in Yaoundé, Cameroon, 2020-2021

Pan African Medical Journal - Conference Proceedings. 2023:18(153).03 Oct 2023.
doi: 10.11604/pamj-cp.2023.18.153.2266
Archived on: 03 Oct 2023
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Keywords: ARI, Cameroon, co-infections, influenza, RSV, SARS-CoV-2
Oral presentation

Viral co-infection with human respiratory syncytial virus in suspected acute and severe respiratory tract infections during COVID-19 pandemic in Yaoundé, Cameroon, 2020-2021

Moïse Henri Moumbeket Yifomnjou1,&, Richard Njouom1

1Centre Pasteur du Cameroun, Yaoundé, Cameroun

&Corresponding author

Introduction: acute lower respiratory tract infections (ALRIs) are one of the leading causes of morbidity and mortality among people of all ages worldwide, particularly in low- and middle-income countries (LMICs). The purpose of this study was to determine epidemiological characteristics of respiratory viruses in acute respiratory infection (ARI) patients during the COVID-19 pandemic in Yaoundé.

Methods: patients were monitored for respiratory symptoms as part of the surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viral infections. Patients of all ages with respiratory symptoms less than 5 days were considered. Sociodemographic and clinical data as well as nasopharyngeal samples was collected from patients. Nasopharyngeal samples were tested for SARS-CoV-2, influenza, and respiratory syncytial virus (RSV) using real-time reversetranscription polymerase chain reaction methods. Virus distribution and demographic data were analyzed with R version 2.15.1.

Results: from July 2020 to October 2021, 1120 patients were included. The overall viral detection rate was 32.5%, including 9.5% for RSV, 12.6% for influenza virus and 12.8% for SARS-CoV-2. Co-infections were detected in 6.9% of positive cases. While RSV and influenza virus showed seasonal trends, SARS-CoV-2 was detected throughout the study period.

Conclusion: we found that during the COVID-19 pandemic, respiratory viruses play an important role in the etiology of influenza-like illness in Cameroon, and this observation was true for patients of all ages.